GLP-1 medications like semaglutide have proven to be highly effective for weight loss. Unlike traditional weight loss medications that rely on amphetamines, which can make you jittery and raise heart rate, GLP-1s work by reducing hunger, making it easier to stick to a weight loss plan without battling constant cravings. With these medications, patients often experience significant weight loss by controlling their appetite, learning portion control, and adapting their lifestyle. Clinical evidence shows that many individuals, including those who have struggled with weight loss after procedures like gastric bypass surgery, have seen even greater results with GLP-1 medications. The most impressive part? You’re not constantly fighting hunger, making it easier to maintain a healthy eating routine and achieve lasting weight loss.

GLP-1 medications like semaglutide work by using a naturally occurring protein that helps regulate hunger and satiety. This protein, which is naturally present in our bodies, begins to diminish over time. However, with this medication, the protein is replenished and works by targeting the brain, specifically the hippocampus, which controls appetite and feelings of fullness. When you take the medication, it signals your brain that you’re full after just a few bites of food, making it easier to control your eating habits and reduce overall calorie intake. This is why many patients experience effective weight loss without feeling constantly hungry or deprived. It’s a natural, safe way to help your body regain control over your appetite.

With GLP-1 medications like semaglutide, most patients start seeing results very quickly. In fact, many feel the effects as soon as the very next day after their first dose. While you’ll begin on a smaller dose and gradually increase to the full therapeutic dose, even the initial quarter-dose starts to impact your appetite right away. The reduction in hunger and improved satiety will be noticeable early on, giving you a sense of success and motivation right from the start. As you continue with the treatment, the effects will become even more pronounced, helping you achieve your weight loss goals faster.

The amount of weight you can expect to lose with GLP-1 medications like semaglutide varies based on your starting weight and body mass index (BMI). Patients with a higher BMI tend to see faster results, with some losing up to 100 pounds within 12 months. However, if you have a lower BMI or are closer to your ideal weight, the weight loss may be more gradual but still consistent. The medication works effectively across a wide range of body types, with results that are tailored to each individual’s starting point and goals.

At US Fit Clinic, we personalize GLP-1 medications like semaglutide to meet each client’s unique needs. The key protein in the medication targets the brain, specifically the hippocampus, to help you feel full, or reach “satiety,” after just a few bites of food. But we don’t stop there. To enhance results, we may add other beneficial elements, like B-12, which boosts your metabolism and increases energy burn. We create a custom blend that maximizes these effects for each patient, ensuring the treatment is as effective as possible for your individual goals and needs.

The core of this weight loss medication is a short-chain peptide, a naturally occurring protein in the body known as GLP-1 (glucagon-like peptide 1). As we age, the production of GLP-1 naturally decreases, which can contribute to weight gain, especially in individuals with chronic obesity. This medication works by replenishing that protein, helping to control hunger and promote satiety. Additionally, a pharmaceutical blend of B-12 is included to support metabolism and provide a natural boost of energy. Unlike stimulant-based weight loss drugs that can cause jitters, this medication provides a gentle, natural effect that reduces cravings and hunger without the side effects. Together, this blend offers a highly effective, safe, and sustainable solution for weight loss.

Yes, with GLP-1 medications like semaglutide, you will still get your daily nutrition. This medication helps you return to natural portion sizes that your body is designed for. For example, a portion of food is typically the size of the palm of your hand, which may be smaller than what you were used to eating before. As you lose weight and adjust to healthier portion sizes, your body can still absorb the nutrients it needs. For individuals with higher starting weights, like those over 300 pounds, the medication may lead to such significant weight loss that a multivitamin is recommended to prevent any potential deficiencies. However, the goal is not undernourishment—it’s about achieving a balanced, healthy portion size that supports long-term weight loss and overall health.

The qualifications for using GLP-1 medications like semaglutide are very straightforward and are primarily based on safety considerations. To qualify, you must not have a history of thyroid cancer or a rare type of abdominal cancer, as these conditions would disqualify you from using the medication. Additionally, individuals who have had frequent pancreatitis are not eligible for this treatment. However, these conditions are quite rare, and most people will qualify for the medication. It is important to consult with a healthcare provider to ensure the medication is right for you.

The side effect profile of GLP-1 medications like semaglutide is minimal compared to older weight loss drugs, especially those with amphetamine bases, which had serious side effects like rapid heart rate, jitteriness, and uncomfortable symptoms. This medication is a naturally occurring protein, and its side effects are primarily gastrointestinal (GI).

Most patients experience mild GI issues during the first two weeks, such as occasional loose stools. In rare cases, less than 5% of patients may experience nausea, which can be managed with an additional medication. After several months of use, some people might experience occasional constipation or mild indigestion. However, these side effects are generally manageable, and fewer than 5% of patients discontinue the medication due to them.

To minimize side effects, we start patients on a very low dose, gradually increasing it to allow their bodies to adjust. This slow approach helps reduce the likelihood of discomfort, ensuring the medication remains effective with minimal issues.